PARP2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PARP2.
Immunogen
A synthetic peptide corresponding to amino acids 43-59 of human PARP2.
Sequence
QRQESKKMPVAGGKANK
Host
Rabbit
Reactivity
Human
Specificity
Reacts with N-terminus of human PARP 2.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — PARP2
Entrez GeneID
10038Gene Name
PARP2
Gene Alias
ADPRT2, ADPRTL2, ADPRTL3, PARP-2, pADPRT-2
Gene Description
poly (ADP-ribose) polymerase 2
Omim ID
607725Gene Ontology
HyperlinkGene Summary
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq
Other Designations
ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2|poly (ADP-ribose) polymerase family, member 2|poly (ADP-ribosyl) transferase-like 2|poly(ADP-ribose) synthetase
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Interactome
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Pathway
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Disease
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Publication Reference
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PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase.
Amé JC, Rolli V, Schreiber V, Niedergang C, Apiou F, Decker P, Muller S, Höger T, Ménissier-de Murcia J, de Murcia G.
The Journal of Biological Chemistry 1999 Jun; 274(25):17860.
Application：IF, WB-Ce, WB-Re, WB-Tr, Insect, Mouse, NIH/3T3 cells, Recombinant protein, Sf9 cells.
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PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase.
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