MAOB polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MAOB.
Immunogen
A synthetic peptide corresponding to internal region of human MAOB.
Sequence
C-HKARKLARLTKEE
Host
Goat
Theoretical MW (kDa)
58.8
Reactivity
Human
Specificity
This antibody is not expected to cross-react with MAOA.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
MAOB polyclonal antibody (Cat # PAB6899)(0.5 ug/mL) staining of human brain (hippocampus) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MAOB
Entrez GeneID
4129Protein Accession#
NP_000889.3Gene Name
MAOB
Gene Alias
MGC26382
Gene Description
monoamine oxidase B
Omim ID
309860Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq
Other Designations
MAO, brain|MAO, platelet|adrenalin oxidase|tyramine oxidase
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Interactome
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Pathway
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Disease
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Publication Reference
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Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: preferential transmission of the MAO-A 941G allele to affected children.
Domschke K, Sheehan K, Lowe N, Kirley A, Mullins C, O'sullivan R, Freitag C, Becker T, Conroy J, Fitzgerald M, Gill M, Hawi Z.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 2005 Apr; 134B(1):110.
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Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: preferential transmission of the MAO-A 941G allele to affected children.
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