PPY polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
PPY polyclonal antibody (Cat # PAB6810) (3 ug/mL) staining of paraffin embedded human pancreas. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PPY.
Immunogen
A synthetic peptide corresponding to internal region of human PPY.
Sequence
C-TRPRYGKRHKEDT
Host
Goat
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Immunohistochemistry (3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
PPY polyclonal antibody (Cat # PAB6810) (3 ug/mL) staining of paraffin embedded human pancreas. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PPY
Entrez GeneID
5539Protein Accession#
NP_002713.1Gene Name
PPY
Gene Alias
PNP
Gene Description
pancreatic polypeptide
Omim ID
167780Gene Ontology
HyperlinkGene Summary
This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. [provided by RefSeq
Other Designations
pancreatic polypeptide Y
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Interactome
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Pathway
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Disease
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Publication Reference
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The gut and energy balance: visceral allies in the obesity wars.
Badman MK, Flier JS.
Science 2005 Mar; 307(5717):1909.
Application：WB, Human, Mouse, Pancreas.
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The gut and energy balance: visceral allies in the obesity wars.
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