PPY DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PPY DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAAARLCLSLLLLSTCVALLLQPLLGAQGAPLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRYGKRHKEDTLAFSEWGSPHAAVPRELSPLDL
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — PPY
Entrez GeneID
5539GeneBank Accession#
BC032225.2Protein Accession#
AAH32225.1Gene Name
PPY
Gene Alias
PNP
Gene Description
pancreatic polypeptide
Omim ID
167780Gene Ontology
HyperlinkGene Summary
This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. [provided by RefSeq
Other Designations
pancreatic polypeptide Y
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Interactome
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Pathway
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Disease
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