RASAL1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
RASAL1 polyclonal antibody (Cat # PAB6531) (0.3 ug/mL) staining of human thyroid lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of RASAL1.
Immunogen
A synthetic peptide corresponding to human RASAL1.
Sequence
C-QERGKAALGPLGP
Host
Goat
Theoretical MW (kDa)
90
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
RASAL1 polyclonal antibody (Cat # PAB6531) (0.3 ug/mL) staining of human thyroid lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RASAL1
Entrez GeneID
8437Protein Accession#
NP_004649.1Gene Name
RASAL1
Gene Alias
RASAL
Gene Description
RAS protein activator like 1 (GAP1 like)
Omim ID
604118Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. [provided by RefSeq
Other Designations
GAP1 like protein|RAS protein activator like 1|RAS-GTPase-activating protein-like
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Interactome
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Publication Reference
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Restricted tissue expression pattern of a novel human rasGAP-related gene and its murine ortholog.
Allen M, Chu S, Brill S, Stotler C, Buckler A.
Gene 1998 Sep; 218(1-2):17.
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Restricted tissue expression pattern of a novel human rasGAP-related gene and its murine ortholog.
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