CARD6 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
CARD6 polyclonal antibody (Cat # PAB6377, 5 ug/mL) staining of paraffin embedded human pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CARD6.
Immunogen
A synthetic peptide corresponding to human CARD6.
Sequence
ATESTPSEIIERER-C
Host
Goat
Theoretical MW (kDa)
116
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
CARD6 polyclonal antibody (Cat # PAB6377, 5 ug/mL) staining of paraffin embedded human pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CARD6
Entrez GeneID
84674Protein Accession#
NP_115976Gene Name
CARD6
Gene Alias
CINCIN1
Gene Description
caspase recruitment domain family, member 6
Omim ID
609986Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq
Other Designations
CARD-containing inhibitor of Nod1 and Cardiak-induced NF-kB activation|caspase recruitment domain protein 6
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Publication Reference
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CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways.
Stehlik C, Hayashi H, Pio F, Godzik A, Reed JC.
The Journal of Biological Chemistry 2003 Aug; 278(34):31941.
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CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways.
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