CDX2 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
The CDX2 polyclonal antibody (Cat # PAB4714) is used in Western blot to detect CDX2 in placenta tissue lysate.
Western Blot (Transfected lysate)
Western blot analysis of CDX2 (arrow) using rabbit CDX2 polyclonal antibody (Cat # PAB4714) . 293 cell lysate (2 &miceo;g/lane) either nontransfected (Lane 1) or transiently transfected with the CDX2 gene (Lane 2) (Origene Technologies) .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with CDX2 polyclonal antibody (Cat # PAB4714) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CDX2.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CDX2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
The CDX2 polyclonal antibody (Cat # PAB4714) is used in Western blot to detect CDX2 in placenta tissue lysate.Western Blot (Transfected lysate)
Western blot analysis of CDX2 (arrow) using rabbit CDX2 polyclonal antibody (Cat # PAB4714) . 293 cell lysate (2 &miceo;g/lane) either nontransfected (Lane 1) or transiently transfected with the CDX2 gene (Lane 2) (Origene Technologies) .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with CDX2 polyclonal antibody (Cat # PAB4714) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — CDX2
Entrez GeneID
1045Protein Accession#
NP_001256;Q99626Gene Name
CDX2
Gene Alias
CDX-3, CDX3
Gene Description
caudal type homeobox 2
Omim ID
600297Gene Ontology
HyperlinkGene Summary
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
Other Designations
OTTHUMP00000018176|caudal type homeo box transcription factor 2|caudal type homeobox transcription factor 2
-
Interactome
-
Disease
-
Publication Reference
-
Cdx2 as a marker of epithelial intestinal differentiation in the esophagus.
Phillips RW, Frierson HF Jr, Moskaluk CA.
The American Journal of Surgical Pathology 2003 Nov; 27(11):1442.
-
CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene.
Bai YQ, Miyake S, Iwai T, Yuasa Y.
Oncogene 2003 Sep; 22(39):7942.
-
Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression.
Yamamoto H, Bai YQ, Yuasa Y.
Biochemical and Biophysical Research Communications 2003 Jan; 300(4):813.
Application：GSA, Monkey, COS-7 cells.
-
Cdx2 as a marker of epithelial intestinal differentiation in the esophagus.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com