RPS6KA4 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
The RPS6KA4 polyclonal antibody (Cat # PAB4524) is used in Western blot to detect RPS6KA4 in placenta tissue lysate .
Immunofluorescence
Indirect immunofluorescence analysis showed that RPS6KA4 is predominantly localized in the nucleus of parental (10T1/2) and oncogene-transformed (Ciras-3) mouse fibroblasts . Cells were co-stained with DAPI to visualize nucleus compartment . Data is kindly provided by B . Drobic and Dr . J . Davie from University of Manitoba (Winnipeg, Canada) .
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RPS6KA4.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human RPS6KA4.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
ELISA (1:1000)
Western Blot (1:100-500)
Immunofluorescence (1:100-500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
The RPS6KA4 polyclonal antibody (Cat # PAB4524) is used in Western blot to detect RPS6KA4 in placenta tissue lysate .Immunofluorescence
Indirect immunofluorescence analysis showed that RPS6KA4 is predominantly localized in the nucleus of parental (10T1/2) and oncogene-transformed (Ciras-3) mouse fibroblasts . Cells were co-stained with DAPI to visualize nucleus compartment . Data is kindly provided by B . Drobic and Dr . J . Davie from University of Manitoba (Winnipeg, Canada) .Enzyme-linked Immunoabsorbent Assay
-
Gene Info — RPS6KA4
Entrez GeneID
8986Protein Accession#
O75585Gene Name
RPS6KA4
Gene Alias
MSK2, RSK-B
Gene Description
ribosomal protein S6 kinase, 90kDa, polypeptide 4
Omim ID
603606Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
Other Designations
mitogen- and stress-activated protein kinase 2|ribosomal protein S6 kinase alpha 4|ribosomal protein S6 kinase, 90kD, polypeptide 4|ribosomal protein kinase B
-
Interactome
-
Pathway
-
Publication Reference
-
Dynamic changes in histone H3 phosphoacetylation during early embryonic stem cell differentiation are directly mediated by mitogen- and stress-activated protein kinase 1 via activation of MAPK pathways.
Lee ER, McCool KW, Murdoch FE, Fritsch MK.
The Journal of Biological Chemistry 2006 May; 281(30):21162.
-
Dynamic changes in histone H3 phosphoacetylation during early embryonic stem cell differentiation are directly mediated by mitogen- and stress-activated protein kinase 1 via activation of MAPK pathways.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com