COL7A1 polyclonal antibody
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More Files
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Immunohistochemistry
Immunohistochemical staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry
Immunohistochemical staining of human skin shows strong membranous positivity in epidermal cells.
Immunohistochemistry
Immunohistochemical staining of human skeletal muscle shows no positivity in myocytes as expected.
Immunohistochemistry
Immunohistochemical staining of human liver shows no positivity in hepatocytes as expected.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human COL7A1.
Sequence
LTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPAPGASGFRI
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts to COL7A1.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50 - 1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemical staining of human pancreas shows no positivity in exocrine glandular cells as expected.Immunohistochemistry
Immunohistochemical staining of human skin shows strong membranous positivity in epidermal cells.Immunohistochemistry
Immunohistochemical staining of human skeletal muscle shows no positivity in myocytes as expected.Immunohistochemistry
Immunohistochemical staining of human liver shows no positivity in hepatocytes as expected. -
Gene Info — COL7A1
Entrez GeneID
1294Gene Name
COL7A1
Gene Alias
EBD1, EBDCT, EBR1
Gene Description
collagen, type VII, alpha 1
Gene Ontology
HyperlinkGene Summary
This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq
Other Designations
LC collagen|alpha 1 type VII collagen|collagen VII, alpha-1 polypeptide|long chain collagen
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Interactome
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Disease
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