CD74 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of Daudi cell lysate with CD74 polyclonal antibody (Cat # PAB31420).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with CD74 polyclonal antibody (Cat # PAB31420) shows strong membranous and cytoplasmic positivity in germinal center cells and in non-germinal center cells.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CD74.
Immunogen
Recombinant protein corresponding to human CD74.
Sequence
PKPVSKMRMATPLLMQALPMGALPQGPMQNATKYGNMTEDHVMHLLQNADPLKVYPPLKGSFPENLRHLKNTMETIDWKVFESWMHHWLLFEMSRHSLEQKPTDAPPK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Daudi cell lysate with CD74 polyclonal antibody (Cat # PAB31420).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with CD74 polyclonal antibody (Cat # PAB31420) shows strong membranous and cytoplasmic positivity in germinal center cells and in non-germinal center cells. -
Gene Info — CD74
Entrez GeneID
972Protein Accession#
P04233Gene Name
CD74
Gene Alias
DHLAG, HLADG, Ia-GAMMA
Gene Description
CD74 molecule, major histocompatibility complex, class II invariant chain
Omim ID
142790Gene Ontology
HyperlinkGene Summary
major histocompatibility complex
Other Designations
CD74 antigen|CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)|HLA-DR-gamma|Ia-associated invariant chain|MHC HLA-DR gamma chain|gamma chain of class II antigens
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Interactome
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Pathway
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Disease
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Publication Reference
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CD74: a new prognostic factor for patients with malignant pleural mesothelioma.
Otterstrom C, Soltermann A, Opitz I, Felley-Bosco E, Weder W, Stahel RA, Triponez F, Robert JH, Serre-Beinier V.
British Journal of Cancer 2014 Apr; 110(8):2040.
Application：IHC-P, Human, Human biphasic mesothelioma, Human epithelioid mesothelioma, Human tissue microarray, Human sarcomatoid mesothelioma.
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Expression of RCAS1 protein in microglia/macrophages accompanying brain tumours. An immunofluorescence study.
Adamek D, Radwańska E, Gajda M.
Folia Neuropathologica 2009 Jan; 47(3):240.
Application：IF, IHC-P, Human, Human brain tumors, Human glioblastoma multiforme.
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CD74: a new prognostic factor for patients with malignant pleural mesothelioma.
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