TLN1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human lung tissue lysate with TLN1 polyclonal antibody (Cat # PAB30703).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node with TLN1 polyclonal antibody (Cat # PAB30703) shows strong cytoplasmic positivity.
Immunofluorescence
Immunofluorescent staining of A-431 cells with TLN1 polyclonal antibody (Cat # PAB30703) (Green) shows positivity in plasma membrane, cytoplasm and focal adhesion sites.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human TLN1.
Immunogen
Recombinant protein corresponding to human TLN1.
Sequence
LLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVVGGMVDSITQAINQLDEGPMGEPEGSFVDYQTTMVRTAKAIAVTVQEMVTKSNTSP
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human lung tissue lysate with TLN1 polyclonal antibody (Cat # PAB30703).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node with TLN1 polyclonal antibody (Cat # PAB30703) shows strong cytoplasmic positivity.Immunofluorescence
Immunofluorescent staining of A-431 cells with TLN1 polyclonal antibody (Cat # PAB30703) (Green) shows positivity in plasma membrane, cytoplasm and focal adhesion sites. -
Gene Info — TLN1
Entrez GeneID
7094Protein Accession#
Q9Y490Gene Name
TLN1
Gene Alias
ILWEQ, KIAA1027, TLN
Gene Description
talin 1
Omim ID
186745Gene Ontology
HyperlinkGene Summary
This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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