Products

Western Blot (Cell lysate)

Western Blot analysis of Lane 1: NIH-3T3 cell lysate (mouse embryonic fibroblast cells) and Lane 2: NBT-II cell lysate (Wistar rat bladder tumor cells) with ATP6AP2 polyclonal antibody (Cat # PAB30616).

Western Blot (Transfected lysate)

Western Blot analysis of Lane 1: negative control (vector only transfected HEK293T cell lysate) and Lane 2: over-expression lysate (co-expressed with a C-terminal myc-DDK tag in mammalian HEK293T cells) with ATP6AP2 polyclonal antibody (Cat # PAB30616).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum with ATP6AP2 polyclonal antibody (Cat # PAB30616) shows strong cytoplasmic positivity in Purkinje cells and in cells of granular layer.

Immunofluorescence

Immunofluorescent staining of U-2 OS with ATP6AP2 polyclonal antibody (Cat # PAB30616) (Green) shows positivity in nucleus and nucleoli.

Entrez GeneID

10159

Protein Accession#

O75787

Gene Name

ATP6AP2

Gene Alias

APT6M8-9, ATP6IP2, ATP6M8-9, ELDF10, HT028, M8-9, MGC99577, MRXE, MSTP009, XMRE

Gene Description

ATPase, H+ transporting, lysosomal accessory protein 2

Omim ID

300423 300556

Gene Ontology

Hyperlink

Gene Summary

This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq

Other Designations

ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9|ATPase, H+ transporting, lysosomal interacting protein 2|OTTHUMP00000025771|V-ATPase M8.9 subunit|embryonic liver differentiation factor 10|renin receptor|va