FKBP2 polyclonal antibody
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Specification
Product Description
FKBP2 polyclonal antibody raised against recombinant human FKBP2.
Immunogen
Recombinant protein corresponding to amino acids of human FKBP2.
Sequence
RKLQIGVKKRVDHCPIKSRKGDVLHMHYT
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (1:500-1:1000)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of RT-4 cell lysate with FKBP2 polyclonal antibody (Cat# PAB29504) at 1:250 - 1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human thyroid gland with FKBP2 polyclonal antibody (Cat# PAB29504) shows moderate cytoplasmic positivity in glandular cells at 1:500 - 1:1000 dilution.Immunofluorescence
Immunofluorescent staining of PC-3 cells with FKBP2 polyclonal antibody (Cat# PAB29504) under 1-4 ug/mL working concentration shows positivity in plasma membrane. Antibody staining is shown in green. -
Gene Info — FKBP2
Entrez GeneID
2286Protein Accession#
P26885Gene Name
FKBP2
Gene Alias
FKBP-13, PPIase
Gene Description
FK506 binding protein 2, 13kDa
Omim ID
186946Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
FK506 binding protein 2 (13kD)|FK506-binding protein 2 (13kD)|peptidyl-prolyl cis-trans isomerase|proline isomerase|rapamycin-binding protein
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Interactome
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Disease
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