PEG10 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta with PEG10 polyclonal antibody (Cat # PAB29434) shows strong cytoplasmic positivity in a subset of trophoblastic cells.
Immunofluorescence
Immunofluorescent staining of human cell line RH-30 with PEG10 polyclonal antibody (Cat # PAB29434) at 1-4 ug/mL concentration shows positivity in cytoplasm.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human PEG10.
Immunogen
Recombinant protein corresponding to human PEG10.
Sequence
QCIHIERRLARAAAARKPRSPPRALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta with PEG10 polyclonal antibody (Cat # PAB29434) shows strong cytoplasmic positivity in a subset of trophoblastic cells.Immunofluorescence
Immunofluorescent staining of human cell line RH-30 with PEG10 polyclonal antibody (Cat # PAB29434) at 1-4 ug/mL concentration shows positivity in cytoplasm. -
Gene Info — PEG10
Entrez GeneID
23089Gene Name
PEG10
Gene Alias
Edr, HB-1, KIAA1051, MEF3L, Mar2, Mart2, RGAG3
Gene Description
paternally expressed 10
Omim ID
609810Gene Ontology
HyperlinkGene Summary
This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas. [provided by RefSeq
Other Designations
MEF3 like 1|embryonal carcinoma differentiation regulated|retrotransposon gag domain containing 3
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