MAP3K9/MAP3K10 (phospho T312/266) polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue by MAP3K9/MAP3K10 (phospho T312/266) polyclonal antibody (Cat # PAB29212) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human MAP3K9/MAP3K10.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T312/266 of human MAP3K9/MAP3K10.
Host
Rabbit
Theoretical MW (kDa)
121
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of MAP3K9/MAP3K10 only when phosphorylated at threonine 312/266.
Form
Liquid
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (without Mg2+ and Ca2+), (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue by MAP3K9/MAP3K10 (phospho T312/266) polyclonal antibody (Cat # PAB29212) without blocking peptide (A) or preincubated with blocking peptide (B) under 1:50-1:100 dilution. -
Gene Info — MAP3K9
Entrez GeneID
4293Protein Accession#
P80192;Q02779Gene Name
MAP3K9
Gene Alias
MLK1, PRKE1
Gene Description
mitogen-activated protein kinase kinase kinase 9
Omim ID
600136Gene Ontology
HyperlinkOther Designations
mixed lineage kinase 1 (tyr and ser/thr specificity)
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Gene Info — MAP3K10
Entrez GeneID
4294Protein Accession#
P80192;Q02779Gene Name
MAP3K10
Gene Alias
MLK2, MST
Gene Description
mitogen-activated protein kinase kinase kinase 10
Omim ID
600137Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq
Other Designations
MKN28 derived nonreceptor_type serine/threonine kinase|MKN28 kinase|mixed lineage kinase 2
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Interactome
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Pathway
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Disease
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