MAP2K7 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta with MAP2K7 polyclonal antibody (Cat # PAB28466) shows strong cytoplasmic positivity in trophoblastic cells at 1:10-1:20 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant MAP2K7.
Immunogen
Recombinant protein corresponding to amino acids of human MAP2K7
Sequence
LVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKRYETMEV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry(1:10-1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human placenta with MAP2K7 polyclonal antibody (Cat # PAB28466) shows strong cytoplasmic positivity in trophoblastic cells at 1:10-1:20 dilution. -
Gene Info — MAP2K7
Entrez GeneID
5609Protein Accession#
F6WCX7Gene Name
MAP2K7
Gene Alias
Jnkk2, MAPKK7, MKK7, PRKMK7
Gene Description
mitogen-activated protein kinase kinase 7
Omim ID
603014Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq
Other Designations
JNK kinase 2|JNK-activating kinase 2|MAP kinase kinase 7|OTTHUMP00000174397|c-Jun N-terminal kinase kinase 2|dual specificity mitogen-activated protein kinase kinase 7
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Interactome
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Pathway
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