CARD10 polyclonal antibody
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More Files
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Immunohistochemistry
Immunohistochemistry analysis of CARD10 in human kidney tissue with CARD10 polyclonal antibody (Cat # PAB27181) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CARD10.
Immunogen
A synthetic peptide corresponding to 16 amino acids at N-terminus of human CARD10.
Host
Rabbit
Reactivity
Human
Specificity
CARD10 antibody is human specific. At least three isoforms of CARD10 are known to exist; this antibody will only detect isoform 1. CARD10 antibody is predicted not to cross-react with other CARMA proteins.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry analysis of CARD10 in human kidney tissue with CARD10 polyclonal antibody (Cat # PAB27181) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CARD10
Entrez GeneID
29775Protein Accession#
NP_055365Gene Name
CARD10
Gene Alias
BIMP1, CARMA3, MGC142219
Gene Description
caspase recruitment domain family, member 10
Omim ID
607209Gene Ontology
HyperlinkGene Summary
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM
Other Designations
Bcl10 binding protein and activator of NFKB|CARD-containing MAGUK 3 protein|caspase recruitment domain protein 10
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Interactome
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Disease
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