PPHLN1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PPHLN1.
Immunogen
A synthetic peptide corresponding to 16 amino acids at internal region of human PPHLN1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of PPHLN1 in mouse colon tissue with PPHLN1 polyclonal antibody (Cat # PAB25788) at 1 ug/mL in (lane 1) the absence and (lane 2) the presence of blocking peptide.Immunohistochemistry
Immunohistochemical analysis of PPHLN1 in human colon tissue with PPHLN1 polyclonal antibody (Cat # PAB25788) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PPHLN1
Entrez GeneID
51535Protein Accession#
NP_958848Gene Name
PPHLN1
Gene Alias
HSPC206, HSPC232, MGC48786
Gene Description
periphilin 1
Omim ID
608150Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
gastric cancer antigen Ga50
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Interactome
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Disease
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