DEFA1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DEFA1.
Immunogen
A synthetic peptide corresponding to DEFA1.
Host
Rabbit
Reactivity
Human
Specificity
DEFA1 polyclonal antibody detects endogenous levels of DEFA1 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using DEFA1 polyclonal antibody (Cat # PAB25168). -
Gene Info — DEFA1
Entrez GeneID
1667Gene Name
DEFA1
Gene Alias
DEF1, DEFA2, HNP-1, HP-1, MGC138393, MRS
Gene Description
defensin, alpha 1
Omim ID
125220Gene Ontology
HyperlinkGene Summary
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. [provided by RefSeq
Other Designations
OTTHUMP00000196017|defensin, alpha 1, myeloid-related sequence|defensin, alpha 2|myeloid-related sequence
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