SLC29A4 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of PMAT (SLC29A4) (arrow) using rabbit SLC29A4 polyclonal antibody (Cat # PAB2256). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PMAT (SLC29A4) gene (Lane 2) (Origene Technologies).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC29A4.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to amino acids 459-489 at C-terminus of human SLC29A4.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of PMAT (SLC29A4) (arrow) using rabbit SLC29A4 polyclonal antibody (Cat # PAB2256). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PMAT (SLC29A4) gene (Lane 2) (Origene Technologies). -
Gene Info — SLC29A4
Entrez GeneID
222962Protein Accession#
NP_666369;Q8R139Gene Name
SLC29A4
Gene Alias
ENT4, FLJ34923, PMAT
Gene Description
solute carrier family 29 (nucleoside transporters), member 4
Omim ID
609149Gene Ontology
HyperlinkGene Summary
This gene is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000025415|equilibrative nucleoside transporter 4|plasma membrane monoamine transporter
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Disease
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Publication Reference
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Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH.
Barnes K, Dobrzynski H, Foppolo S, Beal PR, Ismat F, Scullion ER, Sun L, Tellez J, Ritzel MW, Claycomb WC, Cass CE, Young JD, Billeter-Clark R, Boyett MR, Baldwin SA.
Circulation Research 2006 Sep; 99(5):510.
Application：IF, WB, Human, Mouse, Rat, Heart, HL-1 cells, HUVECs.
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Identification and characterization of a novel monoamine transporter in the human brain.
Engel K, Zhou M, Wang J.
The Journal of Biological Chemistry 2004 Nov; 279(48):50042.
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Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH.
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