DNAH8 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human nasopharynx with DNAH8 polyclonal antibody (Cat # PAB22154) shows strong cytoplasmic positivity in respiratory epithelial cells at 1:500-1:1000 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant DNAH8.
Immunogen
Recombinant protein corresponding to amino acids of human DNAH8.
Sequence
ILNHKSKHVEEAVRELISIFEQIYEVKYTGKVGKQSEQRKHVVFGSETEEGENNDYEANIVNEFDTHDKEDEFKKECKEVFAFFSHQLLDSLQKATRLSLD
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human nasopharynx with DNAH8 polyclonal antibody (Cat # PAB22154) shows strong cytoplasmic positivity in respiratory epithelial cells at 1:500-1:1000 dilution. -
Gene Info — DNAH8
Entrez GeneID
1769Protein Accession#
Q96JB1Gene Name
DNAH8
Gene Alias
ATPase, FLJ25850, FLJ36115, FLJ36334, hdhc9
Gene Description
dynein, axonemal, heavy chain 8
Omim ID
603337Gene Ontology
HyperlinkGene Summary
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Dynein heavy chains (DHCs) are responsible for force production and ATPase activity and contain a highly conserved catalytic domain with 4 P-loop consensus motifs involved in nucleotide binding. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. Axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH8 is an outer arm axonemal DHC (Chapelin et al., 1997 [PubMed 9256245]; Neesen et al., 1997 [PubMed 9373155]).[supplied by OMIM
Other Designations
OTTHUMP00000017871|OTTHUMP00000039711|dynein, axonemal, heavy polypeptide 8
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Interactome
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Disease
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