Products

Enzyme Immunoassay

Entrez GeneID

Gene Name

TNNC2

Gene Alias

-

Gene Description

troponin C type 2 (fast)

Omim ID

Gene Ontology

Gene Summary

Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq

Other Designations

OTTHUMP00000039531|fast skeletal muscle troponin C|troponin C2, fast

Entrez GeneID

Gene Name

TNNC1

Gene Alias

CMD1Z, TNC, TNNC

Gene Description

troponin C type 1 (slow)

Omim ID

Gene Ontology

Gene Summary

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq

Other Designations

cardiac troponin C|slow twitch skeletal/cardiac muscle troponin C|troponin C, slow|troponin C1, slow