TNNC1 monoclonal antibody, clone 4C2cc
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Specification
Product Description
Mouse monoclonal antibody raised against human TNNC1.
Immunogen
Epitope amino acids 23-29 of human cardiac troponin I.
Host
Mouse
Reactivity
Human
Specificity
None of the antibody has cross-reaction with skeletal muscle troponin I.
Form
Liquid
Purification
Protein A purification
Isotype
IgG2a
Recommend Usage
ELISA
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TNNC1
Entrez GeneID
7134Gene Name
TNNC1
Gene Alias
CMD1Z, TNC, TNNC
Gene Description
troponin C type 1 (slow)
Omim ID
191040Gene Ontology
HyperlinkGene Summary
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq
Other Designations
cardiac troponin C|slow twitch skeletal/cardiac muscle troponin C|troponin C, slow|troponin C1, slow
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Interactome
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