SGK1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of SGK1 in human stomach tissue lysate with SGK1 polyclonal antibody (Cat # PAB19433) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).
Immunohistochemistry
Immunohistochemical staining of human stomach cells with SGK1 polyclonal antibody (Cat # PAB19433) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SGK1.
Immunogen
A synthetic peptide corresponding to 18 amino acids near C-terminus of human SGK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
SGK1 antibody is predicted to not cross-react with other SGK protein family members. At least five isoforms are known to exist.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SGK1 in human stomach tissue lysate with SGK1 polyclonal antibody (Cat # PAB19433) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).Immunohistochemistry
Immunohistochemical staining of human stomach cells with SGK1 polyclonal antibody (Cat # PAB19433) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SGK1
Entrez GeneID
6446Protein Accession#
NP_005618Gene Name
SGK1
Gene Alias
SGK
Gene Description
serum/glucocorticoid regulated kinase 1
Omim ID
602958Gene Ontology
HyperlinkGene Summary
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000017247|serine/threonine protein kinase SGK
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Interactome
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Disease
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