CTNNBL1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CTNNBL1.
Immunogen
A synthetic peptide corresponding to 20 amino acids near C-terminus of human CTNNBL1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist; this antibody will detect all but isoform b.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 and 2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of CTNNBL1 in human brain tissue lysate with CTNNBL1 polyclonal antibody (Cat # PAB19409) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).Immunohistochemistry
Immunohistochemical staining of mouse brain cells with CTNNBL1 polyclonal antibody (Cat # PAB19409) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CTNNBL1
Entrez GeneID
56259Protein Accession#
NP_110517Gene Name
CTNNBL1
Gene Alias
C20orf33, FLJ21108, NAP, NYD-SP19, P14L, PP8304, dJ633O20.1
Gene Description
catenin, beta like 1
Omim ID
611537Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs. In addition, the encoded protein contains Armadillo/beta-catenin-like repeats, which have been implicated in protein-protein interactions. Although the function of this protein has not been determined, the C-terminal portion of the protein has been shown to possess apoptosis-inducing activity. [provided by RefSeq
Other Designations
beta catenin-like 1|nuclear associated protein
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Interactome
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Disease
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Publication Reference
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CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.
Febe van Maldegem, Sarah Maslen, Christopher M. Johnson, Anita Chandra, Karuna Ganesh, Mark Skehel and Cristina Rada.
Nucleic Acids Research 2015 Aug; 43(14):7058.
Application:WB, WB-Tr, Human, Mouse, U2OS, Splenic B cells.
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CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.
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