PIAS3 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of K-562 cells with PIAS3 polyclonal antibody (Cat # PAB19244) at 1 ug/mL dilution.
Immunohistochemistry
Immunohistochemical staining of human breast cancer tissue with PIAS3 polyclonal antibody (Cat # PAB19244) at 5 ug/mL dilution.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of PIAS3.
Immunogen
A synthetic peptide corresponding to 12 amino acids near C-terminus of human PIAS3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of K-562 cells with PIAS3 polyclonal antibody (Cat # PAB19244) at 1 ug/mL dilution.Immunohistochemistry
Immunohistochemical staining of human breast cancer tissue with PIAS3 polyclonal antibody (Cat # PAB19244) at 5 ug/mL dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PIAS3
Entrez GeneID
10401Protein Accession#
NP_006090Gene Name
PIAS3
Gene Alias
FLJ14651, ZMIZ5
Gene Description
protein inhibitor of activated STAT, 3
Omim ID
605987Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000015586|zinc finger, MIZ-type containing 5
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Interactome
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Pathway
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