ANAPC5 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of human kidney tissue with ANAPC5 polyclonal antibody (Cat # PAB19235) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.
Immunohistochemistry
Immunohistochemical staining of rat kidney tissue with ANAPC5 polyclonal antibody (Cat # PAB19235) at 5 ug/mL dilution.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of ANAPC5.
Immunogen
A synthetic peptide corresponding to 17 amino acids near internal region of human ANAPC5.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of human kidney tissue with ANAPC5 polyclonal antibody (Cat # PAB19235) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.Immunohistochemistry
Immunohistochemical staining of rat kidney tissue with ANAPC5 polyclonal antibody (Cat # PAB19235) at 5 ug/mL dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ANAPC5
Entrez GeneID
51433Protein Accession#
Q9UJX4Gene Name
ANAPC5
Gene Alias
APC5
Gene Description
anaphase promoting complex subunit 5
Omim ID
606948Gene Ontology
HyperlinkGene Summary
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq
Other Designations
anaphase-promoting complex subunit 5|cyclosome subunit 5
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Interactome
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Pathway
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