Products

Western Blot (Cell lysate)

Western blot analysis of extracts from K-562 cells, using MRPS18C polyclonal antibody (Cat # PAB17557).
Peptide "+" means "with peptide blocking".

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using MRPS18C polyclonal antibody (Cat # PAB17557).
Peptide "+" means "with peptide blocking".

Immunofluorescence

Immunofluorescence analysis of MCF-7 cells, using MRPS18C polyclonal antibody (Cat # PAB17557).
Peptide "+" means "with peptide blocking".

Enzyme-linked Immunoabsorbent Assay

Entrez GeneID

51023

Protein Accession#

Q9Y3D5

Gene Name

MRPS18C

Gene Alias

CGI-134, FLJ11146, FLJ22967, MRP-S18-1, MRPS18-1

Gene Description

mitochondrial ribosomal protein S18C

Gene Ontology

Hyperlink

Gene Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq

Other Designations

mitochondrial ribosomal protein S18-1