LAMA2 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human placenta tissue using LAMA2 polyclonal antibody (Cat # PAB17543).
Peptide "+" means "with peptide blocking".
Immunofluorescence
Immunofluorescence analysis of NIH/3T3 cells, using LAMA2 polyclonal antibody (Cat # PAB17543).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of LAMA2.
Immunogen
A synthetic peptide corresponding to internal of human LAMA2.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total LAMA2 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human placenta tissue using LAMA2 polyclonal antibody (Cat # PAB17543).
Peptide "+" means "with peptide blocking".Immunofluorescence
Immunofluorescence analysis of NIH/3T3 cells, using LAMA2 polyclonal antibody (Cat # PAB17543).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — LAMA2
Entrez GeneID
3908Protein Accession#
P24043Gene Name
LAMA2
Gene Alias
LAMM
Gene Description
laminin, alpha 2
Gene Ontology
HyperlinkGene Summary
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000017189|laminin M|laminin alpha 2 subunit|merosin heavy chain
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Interactome
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Pathway
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Disease
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