TM4SF1 polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TM4SF1 polyclonal antibody (Cat # PAB17359).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TM4SF1.
Immunogen
A synthetic peptide corresponding to internal of human TM4SF1.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody detects endogenous levels of total TM4SF1 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TM4SF1 polyclonal antibody (Cat # PAB17359).
Peptide "+" means "with peptide blocking". -
Gene Info — TM4SF1
Entrez GeneID
4071Protein Accession#
P30408Gene Name
TM4SF1
Gene Alias
H-L6, L6, M3S1, TAAL6
Gene Description
transmembrane 4 L six family member 1
Omim ID
191155Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq
Other Designations
membrane component, chromosome 3, surface marker 1|transmembrane 4 superfamily member 1|tumor-associated antigen L6
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Interactome
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Publication Reference
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Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody.
Marken JS, Bajorath J, Edwards CP, Farr AG, Schieven GL, Hellstrom I, Hellstrom KE, Aruffo A.
The Journal of Biological Chemistry 1994 Mar; 269(10):7397.
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Cloning and expression of the tumor-associated antigen L6.
Marken JS, Schieven GL, Hellstrom I, Hellstrom KE, Aruffo A.
PNAS 1992 Apr; 89(8):3503.
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Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody.
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