PPP2CB polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells using PPP2CB polyclonal antibody (Cat # PAB16980).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PPP2CB.
Immunogen
A synthetic peptide corresponding to human PPP2CB.
Sequence
KQLNENQVRTL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of total PPP2CB protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM PBS, 0.15 M NaCl, pH 7.2 (0.01% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells using PPP2CB polyclonal antibody (Cat # PAB16980). -
Gene Info — PPP2CB
Entrez GeneID
5516Protein Accession#
P62714Gene Name
PPP2CB
Gene Alias
PP2CB
Gene Description
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
Omim ID
176916Gene Ontology
HyperlinkGene Summary
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
PP2A-beta|protein phosphatase 2, catalytic subunit, beta isoform|protein phosphatase type 2A catalytic subunit|serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform
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Interactome
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Pathway
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Publication Reference
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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.
Janssens V, Goris J.
The Biochemical Journal 2001 Feb; 353(Pt 3):417.
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Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen.
Yu XX, Du X, Moreno CS, Green RE, Ogris E, Feng Q, Chou L, McQuoid MJ, Pallas DC.
Molecular Biology of the Cell 2001 Jan; 12(1):185.
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Carboxyl methylation regulates phosphoprotein phosphatase 2A by controlling the association of regulatory B subunits.
Tolstykh T, Lee J, Vafai S, Stock JB.
The EMBO Journal 2000 Nov; 19(21):5682.
Application：WB, Bovine, Bovine brain extracts.
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Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.
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