KITLG polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of KITLG.
Immunogen
A synthetic peptide corresponding to internal region 18 amino acids of human KITLG.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of KITLG in rat brain tissue lysate with KITLG polyclonal antibody (Cat # PAB16744) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry
Immunohistochemistry of KITLG in mouse brain tissue with KITLG polyclonal antibody (Cat # PAB16744) at 2.5 ug/mL .Enzyme-linked Immunoabsorbent Assay
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Gene Info — KITLG
Entrez GeneID
4254Protein Accession#
P21583Gene Name
KITLG
Gene Alias
DKFZp686F2250, KL-1, Kitl, MGF, SCF, SF, SHEP7
Gene Description
KIT ligand
Omim ID
184745Gene Ontology
HyperlinkGene Summary
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
mast cell growth factor|steel factor|stem cell factor
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Interactome
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Pathway
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Disease
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Publication Reference
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Targeting kit activation: a potential therapeutic approach in the treatment of allergic inflammation.
Jensen BM, Metcalfe DD, Gilfillan AM.
Inflammation & Allergy Drug Targets 2007 Mar; 6(1):57.
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Stem cell factor and its receptor c-Kit as targets for inflammatory diseases.
Reber L, Da Silva CA, Frossard N.
European Journal of Pharmacology 2006 Mar; 533(1-3):327.
Application:ELISA, WB-Ce, Mouse, Mouse mast cells.
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Stem cell factor (c-kit ligand) influences eosinophil recruitment and histamine levels in allergic airway inflammation.
Lukacs NW, Strieter RM, Lincoln PM, Brownell E, Pullen DM, Schock HJ, Chensue SW, Taub DD, Kunkel SL.
Journal of Immunology 1996 May; 156(10):3945.
Application:ELISA, Neutralization, IHC-P, Mouse, Alveolar macrophages, Lungs, Serum.
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Targeting kit activation: a potential therapeutic approach in the treatment of allergic inflammation.
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