YWHAQ polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of YWHAQ expression in HeLa (Lane 1) and Jurkat (Lane 2) whole cell lysates. Using YWHAQ polyclonal antibody (Cat # PAB14303).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of YWHAQ.
Immunogen
A synthetic peptide corresponding to human YWHAQ.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% gelatin, 0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of YWHAQ expression in HeLa (Lane 1) and Jurkat (Lane 2) whole cell lysates. Using YWHAQ polyclonal antibody (Cat # PAB14303).Immunohistochemistry
Immunoprecipitation
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Gene Info — YWHAQ
Entrez GeneID
10971Gene Name
YWHAQ
Gene Alias
14-3-3, 1C5, HS1
Gene Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Omim ID
609009Gene Ontology
HyperlinkGene Summary
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq
Other Designations
14-3-3 protein T-cell|14-3-3 protein tau|14-3-3 protein theta|OTTHUMP00000015730|protein tau|tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide
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Interactome
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Pathway
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Disease
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Publication Reference
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How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis.
Yaffe MB.
FEBS Letters 2002 Feb; 513(1):53.
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14-3-3 proteins; bringing new definitions to scaffolding.
Tzivion G, Shen YH, Zhu J.
Oncogene 2001 Oct; 20(44):6331.
Application：IHC, WB-Tr, Human, Cancers, Mammalian cells.
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14-3-3 proteins: structure, function, and regulation.
Fu H, Subramanian RR, Masters SC.
Annual Review of Pharmacology and Toxicology 2000 Jan; 40:617.
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How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis.
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