CRLF2 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of CRLF2 in human liver tissue lysate with CRLF2 polyclonal antibody (Cat # PAB13267) at (A) 0.5, (B) 1 and (C) 2 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of CRLF2 in human liver tissue with CRLF2 polyclonal antibody (Cat # PAB13267) at 5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CRLF2.
Immunogen
A synthetic peptide corresponding to internal region 19 amino acids of human CRLF2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of CRLF2 in human liver tissue lysate with CRLF2 polyclonal antibody (Cat # PAB13267) at (A) 0.5, (B) 1 and (C) 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of CRLF2 in human liver tissue with CRLF2 polyclonal antibody (Cat # PAB13267) at 5 ug/mL . -
Gene Info — CRLF2
Entrez GeneID
64109Protein Accession#
Q9HC73Gene Name
CRLF2
Gene Alias
CRL2, CRLF2Y, TSLPR
Gene Description
cytokine receptor-like factor 2
Gene Ontology
HyperlinkGene Summary
Cytokine signals are mediated through specific receptor complexes, the components of which are mostly members of the type I cytokine receptor family. Type I cytokine receptors share conserved structural features in their extracellular domain. Receptor complexes are typically heterodimeric, consisting of alpha chains, which provide ligand specificity, and beta (or gamma) chains, which are required for the formation of high-affinity binding sites and signal transduction.[supplied by OMIM
Other Designations
cytokine receptor CRL2 precusor|thymic stromal lymphopoietin receptor|thymic stromal-derived lymphopoietin receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Molecular cloning and biological characterization of a novel murine lymphoid growth factor.
Sims JE, Williams DE, Morrissey PJ, Garka K, Foxworthe D, Price V, Friend SL, Farr A, Bedell MA, Jenkins NA, Copeland NG, Grabstein K, Paxton RJ.
The Journal of Experimental Medicine 2000 Sep; 192(5):671.
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Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor.
Park LS, Martin U, Garka K, Gliniak B, Di Santo JP, Muller W, Largaespada DA, Copeland NG, Jenkins NA, Farr AG, Ziegler SF, Morrissey PJ, Paxton R, Sims JE.
The Journal of Experimental Medicine 2000 Sep; 192(5):659.
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Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism.
Levin SD, Koelling RM, Friend SL, Isaksen DE, Ziegler SF, Perlmutter RM, Farr AG.
The Journal of Immunology 1999 Jan; 162(2):677.
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Molecular cloning and biological characterization of a novel murine lymphoid growth factor.
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