HIF1AN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HIF1AN.
Immunogen
A synthetic peptide corresponding to C-terminus of human HIF1AN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody is specific to FIH-1 protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:100)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Detection of HIF1AN in rat brain tissue using HIF1AN polyclonal antibody (Cat # PAB12417) (1 : 100).Immunoprecipitation
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Gene Info — HIF1AN
Entrez GeneID
55662Protein Accession#
Q9NWT6Gene Name
HIF1AN
Gene Alias
DKFZp762F1811, FIH1, FLJ20615, FLJ22027
Gene Description
hypoxia inducible factor 1, alpha subunit inhibitor
Omim ID
606615Gene Ontology
HyperlinkGene Summary
O
Other Designations
OTTHUMP00000020284|Peptide-aspartate beta-dioxygenase|factor inhibiting HIF1|hypoxia-inducible factor 1, alpha subunit inhibitor
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Interactome
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Disease
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Publication Reference
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Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.
Zheng X, Linke S, Dias JM, Zheng X, Gradin K, Wallis TP, Hamilton BR, Gustafsson M, Ruas JL, Wilkins S, Bilton RL, Brismar K, Whitelaw ML, Pereira T, Gorman JJ, Ericson J, Peet DJ, Lendahl U, Poellinger L.
PNAS 2008 Mar; 105(9):3368.
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Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux.
Li J, Wang E, Dutta S, Lau JS, Jiang SW, Datta K, Mukhopadhyay D.
Molecular and Cellular Biology 2007 Oct; 27(20):7345.
Application:WB-Tr, Human, 786-O RCC cells.
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Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors.
Birle DC, Hedley DW.
Cancer Research 2007 Feb; 67(4):1735.
Application:IP, WB, Human, SiHa cells.
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MMP-2 and MMP-9 increase the neurite-promoting potential of schwann cell basal laminae and are upregulated in degenerated nerve.
Ferguson TA, Muir D.
Molecular and Cellular Neurosciences 2000 Aug; 16(2):157.
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Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.
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