PLIN3 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of PLIN3 in 3T3-L1 lysate using PLIN3 polyclonal antibody (Cat # PAB12391).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PLIN3.
Immunogen
A synthetic peptide corresponding to amino acids 350-435 of human PLIN3.
Host
Rabbit
Reactivity
Human, Mouse, Pig, Primates
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PLIN3 in 3T3-L1 lysate using PLIN3 polyclonal antibody (Cat # PAB12391). -
Gene Info — PLIN3
Entrez GeneID
10226Protein Accession#
O60664Gene Name
PLIN3
Gene Alias
MGC11117, MGC2012, PP17, TIP47, M6PRBP1
Gene Description
mannose-6-phosphate receptor binding protein 1
Omim ID
602702Gene Ontology
HyperlinkGene Summary
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene
Other Designations
MPR-BINDING PROTEIN, 47-KD|MPR-binding protein 47 kDa|cargo selection protein (mannose 6 phosphate receptor binding protein)|cargo selection protein TIP47|mannose 6 phosphate receptor binding protein 1|placental protein 17|tail-interacting protein, 47 kD
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Interactome
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Publication Reference
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Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina.
Imanishi Y, Sun W, Maeda T, Maeda A, Palczewski K.
The Journal of Biological Chemistry 2008 Sep; 283(36):25091.
Application：WB-Ti, Mouse, Mouse heart, white adipose tissue (WAT) homogenates, retinal pigmented epithelium.
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S3-12, Adipophilin, and TIP47 package lipid in adipocytes.
Wolins NE, Quaynor BK, Skinner JR, Schoenfish MJ, Tzekov A, Bickel PE.
The Journal of Biological Chemistry 2005 May; 280(19):19146.
Application：IF, WB-Tr, Human, Mouse, 3T3-L1, HeLa, HIB-1B cells.
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TIP47: a cargo selection device for mannose 6-phosphate receptor trafficking.
Diaz E, Pfeffer SR.
Cell 1998 May; 93(3):433.
Application：IF, WB-Ce, Human, Monkey, Cow, K562, EBTr, COS cells.
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Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina.
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