S100A6 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant S100A6.
Immunogen
Recombinant protein corresponding to full length human S100A6.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In antiserum (0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of S100A6 in HeLa whole cell extracts with S100A6 polyclonal antibody (Cat # PAB12046). -
Gene Info — S100A6
Entrez GeneID
6277Protein Accession#
P06703Gene Name
S100A6
Gene Alias
2A9, 5B10, CABP, CACY, PRA
Gene Description
S100 calcium binding protein A6
Omim ID
114110Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq
Other Designations
OTTHUMP00000015472|OTTHUMP00000015473|S100 calcium-binding protein A6|S100 calcium-binding protein A6 (calcyclin)|calcyclin|prolactin receptor-associated protein
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Interactome
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Disease
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Publication Reference
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Expression of S100A6 in cardiac myocytes limits apoptosis induced by tumor necrosis factor-alpha.
Tsoporis JN, Izhar S, Parker TG.
The Journal of Biological Chemistry 2008 Oct; 283(44):30174.
Application:WB, Rat, Rat aortic smooth muscle cells, fibroblasts, neonatal cultured myocytes.
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Expression of S100A6 in cardiac myocytes limits apoptosis induced by tumor necrosis factor-alpha.
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