SIRT6 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of SIRT6 in HeLa whole cell lysate with SIRT6 polyclonal antibody (Cat # PAB12036).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SIRT6.
Immunogen
A synthetic peptide corresponding to amino acids 300-355 of human SIRT6.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of SIRT6 in HeLa whole cell lysate with SIRT6 polyclonal antibody (Cat # PAB12036). -
Gene Info — SIRT6
Entrez GeneID
51548Protein Accession#
Q8N6T7Gene Name
SIRT6
Gene Alias
SIR2L6
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
Omim ID
606211Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq
Other Designations
sir2-related protein type 6|sirtuin 6|sirtuin type 6
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Interactome
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Publication Reference
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Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I.
Molecular Biology of the Cell 2005 Oct; 16(10):4623.
Application：IF, WB, Human, HeLa, NHF, WI-38 cells.
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Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins.
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