DIABLO polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of human DIABLO polyclonal antibody (Cat # PAB0847) expression in HL-60 whole cell lysates.
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Specification
Product Description
Rabbit polyclonal antibody raised against a synthetic peptide of DIABLO.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human DIABLO.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% gelatin, 0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of human DIABLO polyclonal antibody (Cat # PAB0847) expression in HL-60 whole cell lysates. -
Gene Info — DIABLO
Entrez GeneID
56616Gene Name
DIABLO
Gene Alias
DIABLO-S, FLJ10537, FLJ25049, SMAC, SMAC3
Gene Description
diablo homolog (Drosophila)
Omim ID
605219Gene Ontology
HyperlinkGene Summary
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq
Other Designations
0610041G12Rik|diablo|direct IAP-binding protein with low pI|mitochondrial Smac protein|second mitochondria-derived activator of caspase
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Interactome
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Disease
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Publication Reference
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Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.
Kim JS, Eom JI, Cheong JW, Choi AJ, Lee JK, Yang WI, Min YH.
Clinical Cancer Research 2007 Feb; 13(3):1019.
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Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.
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