MAPK11 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of MAPK11 in 15 ugs of (A) human brain and (B) mouse brain lysate using MAPK11 polyclonal antibody (Cat # PAB0372) at 2 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MAPK11.
Immunogen
A synthetic peptide corresponding to amino acids 39-59 of human MAPK11.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.2% gelatin, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of MAPK11 in 15 ugs of (A) human brain and (B) mouse brain lysate using MAPK11 polyclonal antibody (Cat # PAB0372) at 2 ug/mL . -
Gene Info — MAPK11
Entrez GeneID
5600Protein Accession#
NP_002742Gene Name
MAPK11
Gene Alias
P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta
Gene Description
mitogen-activated protein kinase 11
Omim ID
602898Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. [provided by RefSeq
Other Designations
OTTHUMP00000196655|mitogen-activated protein kinase p38 beta|mitogen-activated protein kinase p38-2|stress-activated protein kinase-2|stress-activated protein kinase-2b
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Interactome
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Pathway
- Amyotrophic lateral sclerosis (ALS)
- Epithelial cell signaling in Helicobacter pylori infection
- Fc epsilon RI signaling pathway
- GnRH signaling pathway
- Leukocyte transendothelial migration
- MAPK signaling pathway
- Neurotrophin signaling pathway
- T cell receptor signaling pathway
- Toll-like receptor signaling pathway
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Disease
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