IL24 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of IL24 in the A) absence and B) presence of blocking peptide in Jurkat cell lysate. Using IL24 polyclonal antibody (Cat # PAB0345) at 0.5 ug/mL .
Flow Cytometry
Cell-surface flow cytometry analysis of IL24 in Jurkat cells. Using IL24 polyclonal antibody (Cat # PAB0345) at 5 ug/10^6 cells. The shaded histogram represents cells only, Green represents isotype control, and purple represents anti-IL24 antibody.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of IL24.
Immunogen
A synthetic peptide corresponding to amino acids 100-150 of human IL24.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In buffer containing 0.05% sodium azide, 0.2% gelatin
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of IL24 in the A) absence and B) presence of blocking peptide in Jurkat cell lysate. Using IL24 polyclonal antibody (Cat # PAB0345) at 0.5 ug/mL .Flow Cytometry
Cell-surface flow cytometry analysis of IL24 in Jurkat cells. Using IL24 polyclonal antibody (Cat # PAB0345) at 5 ug/10^6 cells. The shaded histogram represents cells only, Green represents isotype control, and purple represents anti-IL24 antibody. -
Gene Info — IL24
Entrez GeneID
11009Protein Accession#
NP_006841Gene Name
IL24
Gene Alias
C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7
Gene Description
interleukin 24
Omim ID
604136Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
IL-24 splice variant delE3|IL-24 splice variant delE5|OTTHUMP00000034620|melanoma differentiation association protein 7|suppression of tumorigenicity 16 (melanoma differentiation)
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Interactome
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Pathway
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Disease
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