DAXX polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of DAXX in paraffin-embedded formalin-fixed human mammary gland (female breast) using DAXX polyclonal antibody (Cat # PAB0254) at 1 : 2000. A, normal breast tissue. B, ductal carcinoma in situ (DCIS) . C. invasive neoplasia. DAXX expressed increased sucessively with tumor progression. Hematoxylin-eosin counterstain.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DAXX.
Immunogen
A synthetic peptide corresponding to amino acids 272-291 of human DAXX.
Sequence
ERLINKPGPDTFPDYGDVLR
Host
Rabbit
Reactivity
Bovine, Dog, Human, Monkey, Rat
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In serum (0.05% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of DAXX in paraffin-embedded formalin-fixed human mammary gland (female breast) using DAXX polyclonal antibody (Cat # PAB0254) at 1 : 2000. A, normal breast tissue. B, ductal carcinoma in situ (DCIS) . C. invasive neoplasia. DAXX expressed increased sucessively with tumor progression. Hematoxylin-eosin counterstain.Immunohistochemistry (Frozen sections)
Immunoprecipitation
-
Gene Info — DAXX
Entrez GeneID
1616Gene Name
DAXX
Gene Alias
BING2, DAP6, EAP1, MGC126245, MGC126246
Gene Description
death-domain associated protein
Omim ID
603186Gene Ontology
HyperlinkGene Summary
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
CENP-C binding protein|ETS1-associated protein 1|Fas-binding protein|OTTHUMP00000029289|OTTHUMP00000029290|death-associated protein 6
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com