LILRB1 (Human) Recombinant Protein
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More Files
- More Functions
Enzyme-linked Immunoabsorbent Assay
Immobilized Human LILRB1, mFc Tag at 0.5 ug/mL (100 uL/well) on the plate. Dose response curve for Anti-LILRB1 Antibody, hFc Tag with the EC50 of 9.4 ng/mL determined by ELISA.
SEC-HPLC
The purity of-Human LILRB1 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human LILRB1 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
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Specification
Product Description
Human LILRB1 (Q8NHL6-1, Gly24-His458) partial recombinant protein with mFc tag at C-Terminus expressed in HEK293 cells.
Sequence
Gly24-His458
Host
Human
Theoretical MW (kDa)
73.5
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The EC50 was 9.4 ng/mL, messured by ELISA at 0.5 ug/mL.
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of-Human LILRB1 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human LILRB1 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human LILRB1, mFc Tag at 0.5 ug/mL (100 uL/well) on the plate. Dose response curve for Anti-LILRB1 Antibody, hFc Tag with the EC50 of 9.4 ng/mL determined by ELISA.Functional Study
SDS-PAGE
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Gene Info — LILRB1
Entrez GeneID
10859Protein Accession#
Q8NHL6-1Gene Name
LILRB1
Gene Alias
CD85, CD85J, FLJ37515, ILT2, LIR-1, LIR1, MIR-7, MIR7
Gene Description
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
Omim ID
604811Gene Ontology
HyperlinkGene Summary
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD85 antigen|Ig-like transcript 2|OTTHUMP00000068384|OTTHUMP00000068385|OTTHUMP00000068386|OTTHUMP00000068408|immunoglobulin-like transcript 2|leukocyte Ig-like receptor-1|leukocyte immunoglobulin-like receptor 1|leukocyte immunoglobulin-like receptor sub
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Interactome
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Disease
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