TNFRSF10B (Human) Recombinant Protein
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More Files
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SEC-HPLC
The purity of Human TRAIL R2 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human TRAIL R2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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Specification
Product Description
Human TNFRSF10B (O14763-1, Ile56-Glu182) partial recombinant protein with hFc tag at C-Terminus expressed in HEK293 cells.
Sequence
Ile56-Glu182
Host
Human
Theoretical MW (kDa)
41.1
Form
Liquid
Preparation Method
Mammalian cell (HEK293) expression system
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of Human TRAIL R2 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human TRAIL R2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris pH 7.5 (100mM NaCl and 8% trehalose)
Storage Instruction
Store at -80°C for 12 Month.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Enzyme-linked Immunoabsorbent Assay
Functional Study
SDS-PAGE
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Gene Info — TNFRSF10B
Entrez GeneID
8795Protein Accession#
O14763-1Gene Name
TNFRSF10B
Gene Alias
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Gene Description
tumor necrosis factor receptor superfamily, member 10b
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq
Other Designations
Fas-like protein|OTTHUMP00000123492|TNF-related apoptosis-inducing ligand receptor 2|TRAIL receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|d
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Interactome
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Pathway
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Disease
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