CD27 (Human) Recombinant Protein
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Specification
Product Description
Human CD27 (P26842, 21 a.a. - 191 a.a.) partial recombinant protein with His tag at N-terminus expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSHMTPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQRSLCSSDFIR
Host
Escherichia coli
Theoretical MW (kDa)
21.8
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 90.0% by SDS-PAGE
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In 20mM Tris-HCl pH 8.0 (0.4 M Urea and 10% glycerol)
Storage Instruction
Store at 4°C for 2-4 weeks. Store at -20°C for long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — CD27
Entrez GeneID
939Protein Accession#
P26842Gene Name
CD27
Gene Alias
MGC20393, S152, T14, TNFRSF7, Tp55
Gene Description
CD27 molecule
Omim ID
186711Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq
Other Designations
CD27 antigen|CD27L receptor|T cell activation antigen CD27|T cell antivation antigen S152|tumor necrosis factor receptor superfamily, member 7
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