CD27 (Human) Recombinant Protein

Catalog # P7890

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Size:500 ug
Price: USD $ 1,658.00
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  • +1-909-264-1399
    +1-909-992-0619
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  • +1-909-992-3401
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QC Test

SDS-PAGE analysis of CD27 (Human) Recombinant Protein.

Note

  • Specification

    Product Description

    Human CD27 (P26842, 20 a.a. - 191 a.a.) partial recombinant protein with hIgG-His tag expressed in HEK293 cells.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro

    Sequence

    ATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQRSLCSSDFIRLEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH

    Host

    Human

    Theoretical MW (kDa)

    46.2

    Form

    Liquid

    Preparation Method

    Mammalian cell (HEK 293) expression system

    Purity

    > 95% as analyzed by SDS-PAGE.

    Endotoxin Level

    < 1 EU/ug of protein by the LAL method.

    Activity

    ED50 < 0.8 ug/mL, measured by the binding ability in a functional ELISA with Human CD27 Ligand/TNFSF7.

    Quality Control Testing

    SDS-PAGE Stained with Coomassie Blue.

    SDS-PAGE analysis of CD27 (Human) Recombinant Protein.

    Recommend Usage

    Biological Activity
    SDS-PAGE
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4 ( 10% glycerol)

    Storage Instruction

    Store at 4°C for 1 week. For long term storage store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

  • Applications

    Functional Study

    SDS-PAGE

  • Gene Info — CD27

    Entrez GeneID

    939

    Protein Accession#

    P26842

    Gene Name

    CD27

    Gene Alias

    MGC20393, S152, T14, TNFRSF7, Tp55

    Gene Description

    CD27 molecule

    Omim ID

    186711

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq

    Other Designations

    CD27 antigen|CD27L receptor|T cell activation antigen CD27|T cell antivation antigen S152|tumor necrosis factor receptor superfamily, member 7

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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