CCL18 (Human) Recombinant Protein
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Specification
Product Description
Human CCL18 (P55774, 21 a.a. - 89 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
AQVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKPGVILLTKRGRQICADPNKKWVQKYISDLKLNA
Host
Escherichia coli
Theoretical MW (kDa)
7.8
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 97.0% by SDS-PAGE
Activity
The Biological activity is 1 - 10 ng/mL, was calculated by the ability to chemoattract primary Human T lymphocytes, corresponding to a specific activity of 100000 - 1000000 IU/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL18
Entrez GeneID
6362Protein Accession#
P55774Gene Name
CCL18
Gene Alias
AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18
Gene Description
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
Omim ID
603757Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq
Other Designations
CC chemokine ligand 18|alternative macrophage activation-associated CC chemokine 1|chemokine (C-C), dendritic|dendritic cell chemokine 1|macrophage inflammatory protein 4|pulmonary and activation-regulated chemokine|small inducible cytokine A18|small indu
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