CXCL13 (Human) Recombinant Protein
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Specification
Product Description
Human CXCL13 (O43927, 23 a.a. - 109 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
VLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP
Host
Escherichia coli
Theoretical MW (kDa)
10.3
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 97.0% by SDS-PAGE
Activity
The Biological activity is 1 - 10 ng/mL, was determined by the ability to chemoattract human B cells, corresponding to a specific activity of 100000 - 1000000 IU/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CXCL13
Entrez GeneID
10563Protein Accession#
O43927Gene Name
CXCL13
Gene Alias
ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
Gene Description
chemokine (C-X-C motif) ligand 13
Omim ID
605149Gene Ontology
HyperlinkGene Summary
B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq
Other Designations
B-cell chemoattractant|B-cell-attracting chemokine 1|B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)|B-lymphocyte chemoattractant|chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)|small inducible cytokine B subfamily (Cys-X-Cys
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