CXCL13 (Human) Recombinant Protein
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Specification
Product Description
Human CXCL13 (Q53X90, Val 22 - Phe 109) partial recombinant protein expressed in Escherichia coli.
Sequence
Val 22 - Phe 109
Host
Escherichia coli
Theoretical MW (kDa)
10
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purification
Ion exchange column and HPLC reverse phase column
Purity
> 90% by SDS-PAGE and HPLC
Endotoxin Level
< 0.1 ng/ug (1 EU/ug)
Activity
Determined by the ability to chemoattract human T cells using a concentration range of 2.0-10.0 ng/mL.
Storage Buffer
Lyophilized from 20 mM PB, 100 mM NaCl, pH 7.5
Storage Instruction
Store at -20°C on dry atmosphere for 2 years.
After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CXCL13
Entrez GeneID
10563Protein Accession#
Q53X90Gene Name
CXCL13
Gene Alias
ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
Gene Description
chemokine (C-X-C motif) ligand 13
Omim ID
605149Gene Ontology
HyperlinkGene Summary
B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq
Other Designations
B-cell chemoattractant|B-cell-attracting chemokine 1|B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)|B-lymphocyte chemoattractant|chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)|small inducible cytokine B subfamily (Cys-X-Cys
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