TNFRSF17 (Human) Recombinant Protein
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Specification
Product Description
Human TNFRSF17 partial recombinant protein with His tag in N-terminus expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSRKINSEPLKDEFKNTGSGLLGMANIDLEKSRTGDEIILPRGLEYTVEECTCEDCIKSKPKVDSDHCFPLPAMEEGATILVTTKTNDYCKSLPAALSATEIEKSISAR
Host
Escherichia coli
Theoretical MW (kDa)
14.1
Form
Liquid
Preparation Method
Escherichia coli expression system
Purification
chromatographic
Purity
> 90% as determined by SDS-PAGE.
Storage Buffer
Solution containing 20 mM Tris-HCl, pH 8.0, 10% glycerol, 1 mM DTT, 0.15 M NaCl.
Storage Instruction
Store at 4°C for one weeks and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — TNFRSF17
Entrez GeneID
608Protein Accession#
Q02223Gene Name
TNFRSF17
Gene Alias
BCM, BCMA, CD269
Gene Description
tumor necrosis factor receptor superfamily, member 17
Omim ID
109545Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq
Other Designations
B cell maturation antigen|B-cell maturation factor|OTTHUMP00000160261
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